Perimenopause, Gut Health & Hormones: Estrogen, Immunity, and What Most Doctors Miss

Cynthia Thurlow, NP nearly lost her colon—and what followed wasn’t just a medical crisis. It was a collision between biology and a system that wasn’t built to see it.

In this conversation, we go beyond the surface of perimenopause and into what’s actually happening: immune disruption, gut breakdown, and the quiet ways women are dismissed at the exact moment their physiology is shifting the most.

This is not just about hormones. It’s about understanding the signals most women are taught to ignore—and what happens when you finally stop.

This conversation is grounded in the work behind her new book, The Menopause Gut, where she reframes midlife health through the lens of the microbiome.


What You’ll Learn

  • Why perimenopause affects more than hormones
  • The connection between estrogen and immune function
  • How gut health changes in midlife
  • The role of the estrobolome in estrogen metabolism
  • Why protein and nutrition matter more than ever
  • How to advocate for yourself in medical settings

Resources & Links

Cynthia Thurlow is a nurse practitioner, host of the Everyday Wellness podcast, author and international speaker, with over 15 million views for her second TEDx talk on Intermittent Fasting

Her latest book The Menopause Gut is out now. Buy your copy 

Find Cynthia Thurlow on Instagram, Youtube, Substack or her Everyday Wellness Podcast

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