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Estrogen, Progesterone, and Testosterone: How These Hormones Shape Your Daily Life

Let’s take a tour beyond the myths and into the molecular reality of what these hormones really do in your daily life. Estrogen: The Multitasking Mastermind Estrogen isn’t just about periods and PMS. It’s a group of hormones—estradiol, estrone, and estriol—that influence nearly every system in your body. Produced primarily in the ovaries (or via…

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PCOS and Endometriosis: Decoding the Hormonal Mysteries Behind Common Women’s Health Challenges

Despite affecting millions of women, polycystic ovary syndrome (PCOS) and endometriosis remain among the most underdiagnosed, misunderstood, and mismanaged conditions in modern medicine. These aren’t just “period problems” or fertility issues—they are full-body hormonal syndromes with systemic ripple effects that often begin in adolescence with consequences that extend past menopause. PCOS is the most common…

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PCOS: Autonomic Nervous System Dysregulation and Mitochondrial Issues

Women with polycystic ovary syndrome (PCOS) often have increased stress, with an exaggerated sympathetic (fight-flight-freeze-fawn) nervous system and underactive parasympathetic (stay-and-play, rest-and-digest, feed-and-breed!) nervous system. We call these findings autonomic imbalances, including reduced parasympathetic activity, which suggests a potential link to mitochondrial dysfunction. Research indicates that mitochondrial dysfunction is indeed associated with PCOS and may contribute…

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Today Show Appearances

Dr. Sara (Gottfried) Szal MD